MR Fingerprinting in Epilepsy
- Epilepsy affects 65 million people worldwide; approximately 30% of them do not respond to medications but can be cured by surgery. Focal cortical dysplasia, a major pathology for medically intractable epilepsies, are frequently missed by visual analysis of the conventional MRI, making surgical treatment very difficult. Here we propose to develop and validate novel, noninvasive and quantitative MRI acquisition and post-processing techniques, in order to guide epilepsy surgery and make more patients seizure-free.
Collaborators & Funding : NIH NINDS, Cleveland Clinic Epilepsy Center
- - Ma D, Jones SE, Deshmane A, Sakaie K, Pierre EY, Larvie M, McGivney D, Blümcke I, Krishnan B, Lowe M, Gulani V, Najm I, Griswold MA, Wang ZI. Development of high-resolution 3D MR fingerprinting for detection and characterization of epileptic lesions. J Magn Reson Imaging. 2018 Dec 23; PubMed PMID: 30582254.